How Long Does Xanax Last

How Many Hours Does The Effect Of Taking Xanax Last?


Today, buying Xanax online is not a problem. And thanks to the fast delivery, the courier will deliver the drug to the door of your home overnight (24/7). Alprazolam begins to act 30 minutes after oral administration of 1 pill. He perfectly fights anxiety and panic attacks. But how long does Xanax last? It all depends on the individual and the dosage of Xanax (0.25 mg, 1 mg or 2 mg – there are different options). But as a rule, the effect of Alprazolam lasts several hours.

But how long does Xanax last?

After oral administration, the active substance is absorbed into the blood and the active phase of Xanax occurs in 1-2 hours. After a single dose of Alprazolam, plasma levels are proportional to the dose administered: at doses from 0.50 to 3.0 mg, levels from 8.0 to 37 ng/ml were observed. During repeated administration of Аlprazolam from 1.5 to 10 mg / day in divided doses, the equilibrium levels were from 18.3 to 100 ng/ml. The half-life of Аlprazolam is 12-15 hours.

Alprazolam and its metabolites are excreted mainly in urine. The predominant metabolites are: alpha-hydroxyalprazolam and benzophenone derived from Alprazolam. The biological activity of alpha-hydroxyalprazolam is approximately half that of Alprazolam; Benzophenone is practically inactive. The level of these metabolites in plasma is very low, but their half-life is similar to that of Alprazolam.

Alprazolam did not affect prothrombin time or plasma warfarin levels in studies on volunteers who were orally administered warfarin sodium. In vitro, protein binding (human serum protein) to Аlprazolam is 80%. When pregnant mice were injected with carbon-labeled 14 Аlprazolam, it seemed to be evenly distributed in the fetus with a carbon concentration of 14, almost equal to that in the blood and muscles of the mother. The level of these metabolites in plasma is very low, but their half-life is similar to that of Аlprazolam.

How long does the Xanax stay in the body?

As already mentioned, Alprazolam begins to act 30-50 minutes after oral administration, and the maximum activity of the components begins after 1-2 hours. The effect of taking lasts an average of about 5 hours. However, it remains in the blood long after its effects have disappeared. The average half-life is about 11 hours. The half-life of the drug is the time it takes to remove half the dose from the blood. Yes, after 11 hours, Xanax (BUT NOT THE WHOLE DOSE!) Is excreted from the body, and complete cleansing occurs a few weeks after the last pill.

How should I take Xanax?

  • Take Xanax as prescribed by the doctor. Do not increase or decrease the dose yourself. You can not take the drug for longer than the agreed time, even in the case when you buy Xanax 2mg and you still have pills after the course of treatment. Follow the instructions on the medication label. If you have side effects, consult your doctor.
  • Swallow the entire Xanax pill without crushing, chewing, or breaking. This means that if you have been prescribed Xanax 0.25 mg, and you ordered Xanax 1 mg, then drinking ¼ of the pill is prohibited! The dosage of each tablet is specially designed for the slow release of the active component of the drug in the body. If the tablets are crushed or chewed, this can lead to the immediate release of a large amount of the active component!
  • Consult your doctor if Alpazolam does not help in the treatment of anxiety or stress. However, do not stop taking Xanax suddenly: it can lead to withdrawal symptoms or seizures. Ask your doctor for advice on how to avoid Xanax withdrawal syndromes.
  • Store at room temperature and keep away from light, heat and moisture. Make sure that no one except you has access to the drug.

This article is solely educational, encyclopedic and informational functions. You must obtain the approval of your doctor before applying the tips and recommendations described in the article. Do not self-medicate!